Exchange Server 2016 support domain controllers in the forest need to be running one of the following:

Windows Server 2016 Standard or Datacenter

Windows Server 2012 R2 Standard or Datacenter

Windows Server 2012 Standard or Datacenter

Windows Server 2008 R2 Standard or Enterprise

Windows Server 2008 R2 Datacenter RTM or later

Windows Server 2008 Standard, Enterprise, or Datacenter



Supported operating systems for Exchange 2016

Windows Server 2016 Standard or Datacenter*

Windows Server 2012 R2 Standard or Datacenter

Windows Server 2012 Standard or Datacenter



#Supported clients

Outlook 2016

Outlook 2013

Outlook 2010 SP2 and updates KB2956191 and KB2965295

Outlook for Mac for Office 365

Outlook for Mac 2011